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Updated: Jun 7, 2026

Isolation of Intact Eyeball to Obtain Integral Ocular Surface Tissue for Histological Examination and Immunohistochemistry
Published on: October 20, 2019
Epithelial growth over the optic surface of the type 1 Boston Keratoprosthesis: histopathology and implications for
Yousuf M Khalifa1, Don Davis, Nick Mamalis
1Moran Eye Center, University of Utah, Salt Lake City, UT, USA.
Abstract:
We report the histopathology of epithelial overgrowth in the Boston type I keratoprosthesis. The epithelium shows an inconsistent number of layers and basement membrane and goblet cells are absent. Epithelialization of the keratoprosthesis optic would have multiple advantages, but the limitation of vision makes tolerating the overgrowth difficult.
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