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Updated: Jun 7, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Community-acquired methicillin-resistant Staphylococcus aureus necrotizing fasciitis in a healthy adolescent male
Ian J Lalich1, Nadia A Sam-Agudu
1University of North Dakota School of Medicine and Health Sciences, Grand Forks, USA.
Abstract:
Recently, the rate of severe, invasive community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infection has been increasing in healthy children. The single most common cause of necrotizing fasciitis in children is group A Streptococcus. Empiric therapy is usually targeted at this organism, which is uniformly sensitive to penicillin. Necrotizing fasciitis caused by CA-MRSA is a potentially life-threatening infection that has not been extensively reported in the U.S. pediatric population. The limited literature includes reports of neonatal cases and reports of pediatric cases embedded in articles about adults with underlying risk factors. We present a case of CA-MRSA necrotizing fasciitis in a previously healthy 11-year-old male with no risk factors.
Insights
Severe invasive community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is rising in children. This case highlights CA-MRSA necrotizing fasciitis in a healthy child, emphasizing the need for awareness.
Area of Science:
- Pediatric Infectious Diseases
- Microbiology
- Dermatology
Background:
- Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections are increasing in healthy children.
- Necrotizing fasciitis in children is typically caused by Group A Streptococcus, a penicillin-sensitive organism.
- CA-MRSA necrotizing fasciitis is a rare but life-threatening condition in pediatric populations.
Observation:
- A previously healthy 11-year-old male presented with necrotizing fasciitis.
- The patient had no identifiable underlying risk factors for severe infection.
- The causative agent was identified as CA-MRSA.
Findings:
- This case represents a rare instance of CA-MRSA necrotizing fasciitis in an immunocompetent pediatric patient.
- The infection occurred in the absence of typical risk factors, challenging current understanding.
- Prompt diagnosis and management are crucial for favorable outcomes in pediatric CA-MRSA infections.
Implications:
- Highlights the evolving landscape of pediatric infectious diseases and the emergence of CA-MRSA as a significant pathogen.
- Underscores the importance of considering CA-MRSA in the differential diagnosis of severe soft tissue infections in children, even without risk factors.
- Suggests a need for updated clinical guidelines and increased surveillance for CA-MRSA-related invasive infections in the pediatric population.
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