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Potential antitumor agents XVII (1). Cytotoxic agents from indole derivatives and their intermediates
A Andreani1, M Rambaldi, A Locatelli
1Dipartimento di Scienze Farmaceutiche, University of Bologna, Italy.
Acta Pharmaceutica Nordica
|January 1, 1990
Abstract:
New indole derivatives and their intermediates were tested as cytotoxic agents on a culture of P388 leukemia cells. The aldehyde 2a was more active than the thiosemicarbazones 3a, b and the nitrosourea 14. The chloroacetyl derivatives 10, 11 were the most potent cytotoxic agents.