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Updated: Jun 7, 2026

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery
Published on: January 15, 2018
Electrophoretic mobilities of PEGylated gold NPs
Tennyson L Doane1, Yu Cheng, Amir Babar
1Department of Chemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44106, United States.
Abstract:
Electromigration of nanoparticles (NPs) is relevant to many technological and biological applications. We correlate the experimentally observed electromigration of Au NPs with a closed-form theoretical model that furnishes key NP characteristics, including the previously unknown values of Au NP core ζ-potential, PEG-corona permeability, and particle-hydrogel friction coefficient. More generally, the theory furnishes new understanding of NP electromigration in complex environments, establishing a robust and predictive model to guide the design and characterization of functionalized NPs.
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