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[Use of the "Sartorius" cutaneous absorption simulator for transdermal pharmaceutical forms of NSAIDs]
M Valenti1, G L Bandi, C Passarotti
1Gruppo Formenti, Laboratori di Ricerca, Origgio (Va) Italy.
Bollettino Chimico Farmaceutico
|July 1, 1990
Abstract:
We report the results of the in vitro-release of the active ingredients (flurbiprofen and ibuprofen) from dermal form obtained by the Sartorius Absorption simulator SM16750. The results show that the choice of the excipients is basic. Using NSAID, the aqueous gel can be considered the suitable formulation to obtained a good in vitro-release. The quantities of the active ingredients released during the time are plotted in diagrams.