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Drug-eluting tibial stents: objective patency determination
William D McMillan1, Chris D Leville, Troy D Long
1Minneapolis Vascular Physicians and MinneapolisVascular Research Foundation, Plymouth MN 55441, USA. wmcmillan2003@yahoo.com
Journal of Vascular and Interventional Radiology : JVIR
|October 22, 2010
Summary
Drug-eluting tibial stents offer a viable endovascular option for limb-threatening ischemia, demonstrating acceptable patency rates. Close patient surveillance is crucial for successful limb salvage in multilevel treatments.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Endovascular Therapy
Background:
- Limb-threatening ischemia often necessitates intervention for tibial occlusive disease.
- Endovascular management is a key approach for treating critical limb ischemia.
Purpose of the Study:
- To evaluate the patency rates of drug-eluting tibial stents.
- To assess the efficacy of drug-eluting stents in endovascular management of limb-threatening ischemia.
Main Methods:
- Retrospective review of patients treated with drug-eluting tibial stents for limb-threatening ischemia (2004-2008).
- Patients received postprocedural antiplatelet therapy (clopidogrel and aspirin).
- Follow-up included duplex ultrasonography and selective angiography; primary patency, limb salvage, and survival rates were reported.
Main Results:
- Fifty-two patients received drug-eluting tibial stents after suboptimal balloon angioplasty.
- Target lesion patency was 73% at 24 months.
- Limb salvage rate was 86% at 26 months, and survival rate was 65% at 24 months.
Conclusions:
- Drug-eluting tibial stents are a viable endovascular option for limb-threatening ischemia.
- Acceptable patency rates support their use.
- Multilevel treatment and close surveillance are essential for limb salvage.