Related Experiment Video
Updated: Jun 7, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Primary bilateral adrenal diffuse large B-cell lymphoma demonstrating adrenal failure
Kazuhiko Horiguchi1, Koshi Hashimoto, Masayuki Hashizume
1Department of Medicine and Molecular Science, Graduate School of Medicine, Gunma University, Maebashi.
Abstract:
Primary adrenal lymphoma (PAL) is extremely rare although involvement of malignant lymphoma into adrenals is common. We report a case of a 58-year-old man with bilateral PAL who demonstrated adrenal insufficiency. Primary large B-cell lymphoma was proven by a computed tomography-guided needle biopsy of the adrenal tumor. Although a complete remission was once achieved by combination chemotherapy plus rituximab, a recurrence occurred with brain metastasis leading to his death. We concluded that PAL should be considered as a possible cause of bilateral adrenal incidentalomas with progressive adrenal insufficiency.
Related Concept Videos
Adrenal Gland Disorders
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Cushing Syndrome II: Pathophysiology
Cushing Syndrome I: Introduction
Graves Disease II: Pathophysiology
Anatomy of the Adrenal Glands
These glands possess a distinctive yellow tinge due to the stored cholesterol and fatty acids required for hormone synthesis. They are encased in a fibrous capsule and cushioned by fat.
The adrenal gland comprises two distinct regions...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories: