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Enabling GeneHunter as a grid service: a case study for implementing analytical services in biomedical grids.
S Krikov1, R C Price, S A Matney
1Department of Biomedical Informatics, The University of Utah, 26 South 2000 East, Room 5775 HSEB, Salt Lake City, Utah 84108, USA.
Methods of Information in Medicine
|October 22, 2010
Summary
Migrating legacy applications like GeneHunter to a grid service is feasible. Using the caBIG tools and creating a semantic UML model (LinkageX) facilitated integration, demonstrating best practices for biomedical grid services.
Area of Science:
- Biomedical informatics
- Grid computing
Background:
- Biomedical grid literature often focuses on data sharing and new applications.
- Best practices for migrating existing analytical tools to grid environments are less understood.
Purpose of the Study:
- To deploy GeneHunter as a grid service.
- To evaluate the effort and best practices for enabling legacy applications as grid services.
- To address semantic integration challenges using caBIG tools.
Main Methods:
- Utilized general-purpose tools within the caBIG environment for deploying OGSA-compliant services.
- Developed a new UML model, LinkageX, for the LINKAGE data format to achieve semantic integration.
Main Results:
- Successfully achieved semantic integration of GeneHunter within caBIG.
- The LinkageX UML model is publicly available in the caDSR for use with GeneHunter and other programs.
Conclusions:
- Semantic interoperability remains challenging but achievable.
- caBIG tools enhance productivity and reduce errors in grid service deployment for legacy applications.
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