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Hepato-pulmonary amebiasis: a case report.

Vishnu Prasad Shenoy¹, Shashidhar Vishwanath, Bairy Indira

¹Microbiology Department, Kasturba Medical College, Manipal, India. vishnuprasad.shenoy@rediffmail.com

The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases

|October 22, 2010

Summary

This case report highlights a rare instance of hepato-pulmonary amebiasis. Early diagnosis and treatment with amebicides led to a full recovery, emphasizing prompt medical intervention.

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Area of Science:

Infectious Diseases
Parasitology
Clinical Medicine

Background:

Entamoeba histolytica infections are globally prevalent, particularly in tropical regions, with most cases being asymptomatic.
While hepatic involvement is common in extra-intestinal amebiasis, pleuro-pulmonary manifestations are less frequent but often linked to amebic liver abscess.
Pulmonary amebiasis affects approximately 2-3% of patients with invasive Entamoeba histolytica disease.

Observation:

A 45-year-old male presented with symptoms suggestive of hepato-pulmonary amebiasis.
Diagnosis was confirmed through direct sputum examination revealing Entamoeba histolytica trophozoites and positive serology.
The patient exhibited the second most common extra-intestinal pattern of infection.

Findings:

Treatment with metronidazole and chloroquine resulted in significant clinical improvement.
The patient achieved a complete recovery and remained asymptomatic during follow-up.
Microscopic identification of Entamoeba histolytica in sputum was crucial for diagnosis.

Implications:

This case underscores the importance of considering pulmonary amebiasis in patients with suspected invasive Entamoeba histolytica infections, especially those with liver abscess.
Effective collaboration between clinicians and microbiologists is vital for the timely and accurate diagnosis of rare parasitic infections.
Prompt administration of appropriate antiparasitic therapy can lead to favorable patient outcomes in cases of extra-intestinal amebiasis.