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Related Experiment Videos

Selenium supplementation improves mood in a double-blind crossover trial.

D Benton1, R Cook

  • 1Department of Psychology, University College, Swansea, Wales, UK.

Psychopharmacology
|January 1, 1990
PubMed
Summary

This study investigated selenium supplementation in the British population. Selenium intake significantly improved mood state in participants over a 5-week period.

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Area of Science:

  • Nutritional Science
  • Psychology
  • Public Health

Background:

  • Sub-clinical trace element deficiencies can impact population health.
  • Selenium is an essential trace element with known roles in various bodily functions.
  • The mood state of the British population concerning selenium levels was previously unevaluated.

Purpose of the Study:

  • To investigate the potential for sub-clinical selenium deficiency in the British population.
  • To assess the impact of selenium supplementation on mood state.

Main Methods:

  • A double-blind, placebo-controlled crossover study was conducted.
  • Fifty subjects received daily supplementation of either 100 micrograms of selenium or a placebo for 5 weeks.
  • Mood was assessed using the Profile of Mood States (POMS) at three intervals.

Main Results:

  • No significant mood changes were observed in the placebo group.
  • Participants taking selenium reported a substantial improvement in mood state after 2.5 and 5 weeks of supplementation.
  • This suggests a positive effect of selenium on psychological well-being.

Conclusions:

  • Selenium supplementation may alleviate sub-clinical deficiencies impacting mood.
  • Daily selenium intake can lead to significant mood improvements.
  • Further research is warranted to explore selenium's role in mental well-being and its prevalence in deficiency within the UK population.

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