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Repeated Transcranial Magnetic Stimulation Combined with Action Observation Training in Children with Spastic Cerebral Palsy
Published on: August 9, 2024
A comparison of interventions for children with cerebral palsy to improve sitting postural control: a clinical trial
Regina T Harbourne1, Sandra Willett, Anastasia Kyvelidou
1Physical Therapy Department, Munroe Meyer Institute, University of Nebraska Medical Center, 985450 Nebraska Medical Center, Omaha, NE 68198-5450, USA. rharbour@unmc.edu
Insights
A perceptual-motor intervention showed advantages in improving sitting postural control for infants with cerebral palsy (CP), as measured by center-of-pressure (COP) data. Both interventions improved Gross Motor Function Measure (GMFM) scores.
Area of Science:
- Pediatrics
- Neurology
- Rehabilitation
Background:
- Independent sitting is crucial for infant development but often delayed in children with cerebral palsy (CP).
- Limited research exists on interventions specifically targeting sitting ability in infants with CP.
Purpose of the Study:
- To compare two distinct interventions aimed at enhancing sitting postural control in infants diagnosed with or at risk for CP.
Main Methods:
- A randomized longitudinal study involving infants under two years old at risk for CP.
- Participants were assigned to either an 8-week home program or a 2-times-weekly perceptual-motor intervention.
- Center-of-pressure (COP) data and the Gross Motor Function Measure (GMFM) sitting subscale were used for outcome assessment.
Main Results:
- Both intervention groups demonstrated progress on the GMFM sitting subscale.
- Center-of-pressure (COP) measures revealed significant differences between groups, favoring the perceptual-motor intervention.
- COP variables were sensitive in assessing infant postural control and intervention effectiveness.
Conclusions:
- The perceptual-motor intervention demonstrated a measurable advantage in improving postural control compared to the home program, based on COP data.
- While both interventions yielded improvements, COP measures offer a sensitive tool for evaluating infant posture.
- Further research with larger sample sizes is needed to generalize these findings.
Background:
The ability to sit independently is fundamental for function but delayed in infants with cerebral palsy (CP). Studies of interventions directed specifically toward sitting in infants with CP have not been reported.
Objective:
The purpose of this study was to compare 2 interventions for improving sitting postural control in infants with CP.
Design:
For this randomized longitudinal study, infants under 2 years of age and at risk for CP were recruited for intervention directed toward sitting independence.
Setting:
The intervention was conducted at home or at an outpatient facility.
Patients And Intervention:
Fifteen infants with typical development (mean age at entry = 5 months, SD = 0.5) were followed longitudinally as a comparison for postural variables. Thirty-five infants with delays in achieving sitting were recruited. Infants with delays were randomly assigned to receive a home program (1 time per week for 8 weeks; mean age = 15.5 months, SD = 7) or a perceptual-motor intervention (2 times per week for 8 weeks; mean age = 14.3 months, SD = 3).
Measurements:
The primary outcome measure was center-of-pressure (COP) data, from which linear and nonlinear variables were extracted. The Gross Motor Function Measure (GMFM) sitting subsection was the clinical outcome measure.
Results:
There was a main effect of time for the GMFM sitting subscale and for 2 of the COP variables. Interaction of group × time factors indicated significant differences between intervention groups on 2 COP measures, in favor of the group with perceptual-motor intervention.
Limitations:
The small number of infants limits the ability to generalize the findings.
Conclusions:
Although both groups made progress on the GMFM, the COP measures indicated an advantage for the group with perceptual-motor intervention. The COP measures appear sensitive for assessment of infant posture control and quantifying intervention response.
