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Orbital nerve sheath myxoma: a case report
Margarita Sánchez-Orgaz1, Anna Grabowska, Alvaro Arbizu-Duralde
1Service of Ophthalmology, University Hospital, La Paz, Madrid, Spain. msorgaz@gmail.com
Ophthalmic Plastic and Reconstructive Surgery
|October 23, 2010
Summary
A rare nerve sheath myxoma was diagnosed in a 72-year-old man presenting with eyelid ptosis and an orbital mass. This orbital tumor, confirmed by S-100 protein staining, is the first reported case.
Area of Science:
- Ophthalmology
- Oncology
- Pathology
Background:
- Orbital tumors are rare, and their early diagnosis is crucial for preserving vision.
- Ptosis and orbital masses can indicate various underlying pathologies, necessitating thorough investigation.
Observation:
- A 72-year-old male presented with a two-year history of right eye ptosis and a painless lateral orbital mass.
- Orbital magnetic resonance imaging (MRI) identified a well-defined lesion in the superotemporal quadrant.
Findings:
- Surgical excision and subsequent histopathological examination confirmed the lesion as a nerve sheath myxoma.
- The tumor exhibited characteristic myxoid nodules, fibrous septa, and spindle-shaped/stellate cells, with positive S-100 protein immunostaining.
Implications:
- This case represents the first documented instance of a nerve sheath myxoma occurring within the orbit.
- Ophthalmologists and oncologists should consider nerve sheath myxoma in the differential diagnosis of orbital tumors, despite its rarity.