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Updated: Jun 7, 2026
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Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
Published on: June 23, 2019
Efficient microwave-assisted synthesis of 5-deazaflavine derivatives
Jorge Trilleras1, Luis Gabriel López, Dency José Pacheco
1Grupo de Investigación en Compuestos Heterocíclicos, Programa de Química, Facultad de Ciencias Básicas, Universidad del Atlántico, A.A.1890 Barranquilla, Colombia. jorgetrilleras@mail.uniatlantico.edu.co
Molecules (Basel, Switzerland)
|October 23, 2010
Abstract:
A series of pyrimido[4,5-b]quinolines (5-deazaflavines), were synthesized by microwave assisted intramolecular cyclization. The N⁴-substituted-2,4-diamino-6-chloro-pyrimidine-5-carbaldehydes, were prepared by selective monoamination of 2-amino-4,6-dichloropyrimidine-5-carbaldehyde with aliphatic and aromatic amines.
