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Generation of High Quality Chromatin Immunoprecipitation DNA Template for High-throughput Sequencing (ChIP-seq)
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Metagenomic study of single-nucleotide polymorphism within candidate genes associated with type 2 diabetes in an

P N Mukhopadhyaya1, A Acharya, Y Chavan

  • 1Medical Genetics Division, geneOmbio Technologies, Pashan, Pune, Maharashtra, India. pnm6619@gmail.com

Genetics and Molecular Research : GMR
|October 23, 2010
PubMed

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Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
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