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Updated: Jun 7, 2026

Estimation of Urinary Nanocrystals in Humans using Calcium Fluorophore Labeling and Nanoparticle Tracking Analysis
Published on: February 9, 2021
Mass spectrometry and renal calculi
Mircea Penescu1, Victor Lorin Purcarea, Ioana Sisu
1"Carol Davila" Hospital of Nephrology, 4 Calea Grivitei Street, RO-010701 Bucharest, Romania.
Abstract:
The present review represents a concise and complete survey of the literature covering 2004-2009, concerning the mass spectrometric techniques involved in the structural investigation of renal calculi. After a short presentation of the fundamental mass spectrometric techniques (MALDI-TOF, QTOF, MS-MS) as well as hyphenated methods (GC-MS, LC-MS, CE-MS), an extensive study of the urinary proteome analysis as well as the detection and quantification by mass spectrometry of toxins, drugs and metabolites from renal calculi is presented.
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