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Published on: July 20, 2022
Fungal peritonitis among the peritoneal dialysis patients of four Turkish centres
Rumeyza Kazancioglu1, Gulbahar Kirikci, Muserref Albaz
1Department of Nephrology, Haseki Training and Research Hospital, Istanbul, Turkey. drkazancioglu@yahoo.com
Abstract:
This study evaluates the clinical findings and treatment of continuous ambulatory peritoneal dialysis (CAPD) patients with fungal peritonitis in Istanbul from 2000 to 2010. The clinical records of 15 patients with fungal peritonitis among the total 795 patients were reviewed for the clinical and laboratory data. The mean duration of dialysis from the initiation of treatment until the development of fungal peritonitis was 41.14 months. Fungal peritonitis was the primary episode of infection in eight patients. In five other patients previous intensive antibiotherapy was documented. The isolated mircoboes were Candida albicans in six, non-C. albicans in eight and Aspergillus fumigatus in one patient. Tenckoff catheters were removed in all cases and antifungal treatment was given for a minimum of three weeks. Two patients died in the hospital due to the fungal infection whereas others were transferred to haemodialysis. This study highlights the importance of removing the catheter and initiating antifungal therapy as soon as possible in cases of fungal peritonitis because it is responsible for high morbidity and mortality.
Insights
Fungal peritonitis in continuous ambulatory peritoneal dialysis (CAPD) patients is serious. Prompt catheter removal and antifungal treatment are crucial to reduce high morbidity and mortality in CAPD-associated fungal peritonitis.
Area of Science:
- Nephrology
- Infectious Diseases
- Clinical Medicine
Background:
- Fungal peritonitis is a serious complication in continuous ambulatory peritoneal dialysis (CAPD).
- Understanding clinical findings and treatment outcomes is vital for managing CAPD patients.
Purpose of the Study:
- To evaluate the clinical features and treatment strategies for fungal peritonitis in CAPD patients.
- To analyze the outcomes of fungal peritonitis in a specific patient cohort.
Main Methods:
- Retrospective review of clinical and laboratory data for 15 CAPD patients with fungal peritonitis.
- Analysis of causative fungal species, treatment protocols, and patient outcomes.
Main Results:
- The mean duration of dialysis before fungal peritonitis was 41.14 months.
- Candida species were the most common isolates (14/15 patients).
- Catheter removal and antifungal therapy led to transfer to hemodialysis or death in some cases.
Conclusions:
- Early diagnosis, Tenckoff catheter removal, and prompt antifungal therapy are critical for managing fungal peritonitis in CAPD patients.
- Fungal peritonitis in CAPD is associated with significant morbidity and mortality.
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