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Social Defeat Stress Model for Adolescent C57BL/6 Male and Female Mice
Published on: March 15, 2024
Lack of assertion, peer victimization, and risk for depression in girls: testing a diathesis-stress model
Kate Keenan1, Alison Hipwell, Xin Feng
1Department of Psychiatry, University of Chicago, Chicago, Illinois 60637, USA. kekeenan@uchicago.edu
Purpose:
To apply a diathesis × stress model to testing the association between peer victimization and depression in a sample of preadolescent girls.
Methods:
DSM-IV symptoms of depression symptoms were measured at ages 9 and 11, assertiveness and peer victimization were assessed by youth report at age 9.
Results:
The interaction of low levels of assertiveness and high peer victimization at age 9 was predictive of depression symptoms at age 11, controlling for earlier depression symptoms.
Conclusions:
The results extend the published data on peer relations and depression by identifying a group of girls who may be particularly vulnerable to the stress of negative peer interactions.
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