Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Management of Insomnia01:19

Management of Insomnia

The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Sedatives and Hypnotics Drugs: Miscellaneous Agents01:17

Sedatives and Hypnotics Drugs: Miscellaneous Agents

Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
Narcolepsy01:07

Narcolepsy

Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimizing the Better Nights, Better Days for Children with Neurodevelopmental Disorders program for large scale implementation.

Frontiers in sleep·2025
Same author

Child sexual abuse and sleep disturbances among adolescents: the role of post-traumatic stress disorder symptoms.

Frontiers in psychology·2025
Same author

Self-Reported Precipitating and Priming Factors for Somnambulism in Adult Sleepwalkers.

Journal of sleep research·2025
Same author

The Role of Probiotics in Modulating Myocardial Infarction and Depression-like Symptoms: A Study on Sex-Specific Responses.

Biomedicines·2024
Same author

Impact of Pre-Sleep Visual Media Exposure on Dreams: A Scoping Review.

Brain sciences·2024
Same author

The practice of Daylight Saving Time in Canada: Its suitability with respect to sleep and circadian rhythms.

Canadian journal of public health = Revue canadienne de sante publique·2024

Related Experiment Video

Updated: Jun 7, 2026

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

NonREM sleep mentation in chronically-treated persons with schizophrenia.

Félix-Antoine Lusignan1, Roger Godbout, Marie-Josée Dubuc

  • 1Centre de Recherche Fernand-Seguin, Neurodevelopmental Disorders Program, Hôpital Rivière-des-Prairies, 7070 Boulevard Perras, Montréal, Québec, Canada H1E 1A4.

Consciousness and Cognition
|October 26, 2010
PubMed
Summary

Dream content in schizophrenia patients during NonREM sleep was similar to controls, with fewer words and less bizarreness reported compared to REM sleep. This suggests comparable sleep stage cognitive styles between groups.

More Related Videos

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
04:33

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood
08:20

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood

Published on: October 2, 2019

Related Experiment Videos

Last Updated: Jun 7, 2026

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
04:33

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood
08:20

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood

Published on: October 2, 2019

Area of Science:

  • Neuroscience
  • Psychiatry
  • Sleep Medicine

Background:

  • Schizophrenia is a complex mental disorder often associated with altered sleep patterns.
  • Understanding dream content differences between schizophrenia patients and healthy individuals can offer insights into cognitive processes during sleep.

Purpose of the Study:

  • To compare laboratory dream content between patients with schizophrenia and healthy controls, focusing on NonREM sleep.
  • To investigate differences in dream recall, narrative complexity, and subjective bizarreness between sleep stages and groups.

Main Methods:

  • 14 patients with schizophrenia and 15 healthy controls underwent laboratory sleep monitoring.
  • Awakenings from NonREM and REM sleep were performed to elicit dream reports.
  • Dream content was analyzed for narrative length, number of reportable items, and subjective bizarreness.

Main Results:

  • Dream recall frequency was similar between schizophrenia patients and controls for both NonREM and REM sleep.
  • NonREM sleep narratives were shorter in patients with schizophrenia compared to controls.
  • Both groups reported fewer words and less elaborate content in NonREM sleep compared to REM sleep.
  • Healthy controls reported significantly more bizarre REM sleep mentation than NonREM, a difference not seen in schizophrenia patients.

Conclusions:

  • NonREM sleep mentation in schizophrenia patients shows minimal differences compared to controls.
  • Cognitive styles during different sleep stages appear comparable between the groups.
  • NonREM sleep reports are generally more thought-like and less bizarre than REM sleep reports for both patients and controls.