Related Experiment Video
Updated: Apr 15, 2026

Ferric Chloride-induced Murine Thrombosis Models
Published on: September 5, 2016
Are there more tricks in the bag for treating thrombocytopenia?
1Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California 94143-0100, USA. leavitta@labmed2.ucsf.edu
Abstract:
Thrombocytopenia, an abnormally low number of circulating platelets, results from inadequate platelet production, splenic platelet sequestration, or accelerated platelet clearance. Platelet transfusions are now the cornerstone for treating thrombocytopenia. With an ever-expanding demand for platelets, and with many patients having an inadequate response to platelet transfusions, new strategies are needed to treat thrombocytopenia. In this issue of the JCI, Fuentes et al. present provocative data regarding the use of direct megakaryocyte infusions as a novel approach to manage this vexing clinical problem.
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