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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
Comparison of (semi-)automatic and manually adjusted measurements of left ventricular function in dual source
G J de Jonge1, P M A van Ooijen, J Overbosch
1Department of Radiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. g.de.jonge@rad.umcg.nl
The International Journal of Cardiovascular Imaging
|October 26, 2010
Summary
Semi-automatic measurements of left ventricular (LV) function using cardiac dual-source computed tomography (DSCT) are feasible but show significant differences compared to manual analysis. Expert manual correction is recommended for accurate LV functional parameter assessment.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Accurate assessment of left ventricular (LV) function is crucial for diagnosing and managing cardiovascular diseases.
- Cardiac dual-source computed tomography (DSCT) is increasingly used for cardiac imaging.
- Semi-automatic analysis tools aim to streamline the measurement of LV functional parameters, but their accuracy requires validation against manual methods.
Purpose of the Study:
- To evaluate the accuracy of semi-automatic measurements of LV functional parameters (LV ejection fraction, end-systolic volume, end-diastolic volume, myocardial mass) derived from cardiac DSCT.
- To compare the performance of semi-automatic versus manual measurement techniques across three different commercial workstations.
- To determine the time efficiency and inter-observer/intra-observer variability of both measurement approaches.
Main Methods:
- Forty patients undergoing cardiac DSCT were included in this study.
- Multiphase reconstructions were generated at 10% intervals of the RR-interval.
- LV functional parameters were calculated using both semi-automatic and manual adjustment methods on three distinct workstations (Vitrea, Aquarius, Circulation).
Main Results:
- Semi-automatic measurements showed good correlation with manual measurements for most parameters on Vitrea and Aquarius workstations.
- The Circulation workstation demonstrated a weaker correlation for LV ejection fraction (r=0.45).
- Statistically significant differences between semi-automatic and manual measurements were observed for multiple parameters across all three workstations, particularly for LV ejection fraction and end-systolic volume.
Conclusions:
- While semi-automatic measurement of LV functional parameters using cardiac DSCT is feasible, significant discrepancies exist compared to manual assessments.
- The accuracy varies across different workstations, with notable differences observed in LV ejection fraction and end-systolic volume.
- Expert manual correction remains essential for ensuring the reliability and accuracy of LV functional parameter quantification from cardiac DSCT data.

