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Updated: Jun 7, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

Radical nephrectomy via epidural-only anesthesia.

Timothy V Johnson¹, Ninetta Bond, Viraj A Master

¹Department of Urology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

The Canadian Journal of Urology

|October 27, 2010

Summary

This summary is machine-generated.

This study reports the first open radical nephrectomy using only epidural anesthesia. This technique enabled surgery for a patient with kidney cancer and severe emphysema, avoiding general anesthesia risks.

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Area of Science:

Anesthesiology
Urologic Oncology

Background:

Open radical nephrectomy is a standard treatment for localized renal cell carcinoma.
General anesthesia poses risks for patients with severe respiratory comorbidities like emphysema.

Observation:

A patient with localized renal cell carcinoma and severe emphysema required open nephrectomy.
General anesthesia was contraindicated due to the patient's emphysema.

Findings:

The successful performance of an open radical nephrectomy utilizing epidural-only anesthesia is presented.
Epidural anesthesia bypassed the pulmonary system, mitigating risks associated with general anesthesia in this patient.

Implications:

Epidural-only anesthesia offers a viable alternative for high-risk surgical candidates undergoing nephrectomy.
This approach may expand surgical options for patients with cardiorespiratory limitations.