A theory-based problem-solving approach to recruitment challenges in a large randomized field trial

Area of Science:

• Clinical Trials
• Public Health Research
• Biostatistics

Background:

• Large field trials frequently encounter recruitment challenges, impacting study timelines and outcomes.
• Sustaining participant accrual is critical for achieving target enrollment and statistical power.

Purpose of the Study:

• To describe a systematic, theory-based problem-solving approach for addressing recruitment issues in large field trials.
• To demonstrate how continuous strategy implementation can sustain participant accrual.

Main Methods:

• A systematic, theory-based problem-solving framework was employed.
• Research teams actively identified recruitment barriers and implemented adaptive strategies.
• Continuous monitoring and adjustment of strategies were integral to the process.

Main Results:

• The systematic approach facilitated a deeper understanding of recruitment challenges.
• Continuous strategy implementation successfully sustained participant accrual towards the target enrollment.
• Problem-solving enhanced the research team's ability to adapt and overcome obstacles.

Conclusions:

• A structured, theory-based problem-solving methodology is effective for managing recruitment challenges in large field trials.
• Adaptive strategies and continuous monitoring are essential for achieving and sustaining target enrollment in clinical research.