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Predictive relationship between depression and physical functioning after coronary surgery
Friederike Kendel1, Götz Gelbrich, Markus Wirtz
1Institute of Medical Psychology, Charité-Universitätsmedizin Berlin, Germany. friederike.kendel@charite.de
Insights
Depression negatively impacts physical functioning after coronary artery bypass graft (CABG) surgery. Patients with systolic heart failure are particularly vulnerable to this decline, highlighting the need for mental health support post-surgery.
Area of Science:
- Cardiology
- Psychiatry
- Health Psychology
Background:
- Depression is common in patients undergoing coronary artery bypass graft (CABG) surgery.
- Depression is linked to poorer health outcomes in CABG patients.
Purpose of the Study:
- To examine the relationship between depression and physical functioning in CABG patients.
- To identify if depression predicts changes in physical functioning over time.
Main Methods:
- 883 patients undergoing CABG completed the Patient Health Questionnaire (PHQ) for depression and the 36-Item Short-Form Health Survey (SF-36) for physical functioning.
- Assessments occurred pre-surgery (T1), 2 months post-surgery (T2), and 1 year post-surgery (T3).
- Cross-lagged path analysis and multigroup comparisons were used.
Main Results:
- Increased depressive symptoms predicted decreased physical functioning at both 2 months (β = -0.15) and 1 year (β = -0.17) post-surgery.
- This effect was more pronounced in patients with systolic heart failure (left ventricular ejection fraction [LVEF] ≤45%) between 2 months and 1 year post-surgery (β = -0.30).
- Physical functioning did not predict changes in depression.
Conclusions:
- Diagnosis and treatment of depression are crucial for CABG patients.
- Patients with systolic heart failure and depression are at higher risk for physical functioning decline after CABG.
- Targeted interventions for depression may improve physical recovery in this population.
Background:
Depression is a prevalent condition in patients undergoing coronary artery bypass graft surgery (CABG) and is often associated with a less favorable health status. The aim of this study was to investigate the relationship between depression and physical functioning in patients undergoing CABG.
Methods:
The analyses were based on a sample of 883 consecutive subjects (aged 35-93 years; 19.8% women) undergoing CABG. Depression was assessed using the Patient Health Questionnaire (PHQ); the subscale "physical functioning" was taken from the 36-Item Short-Form Health Survey. Questionnaires were administered 1 to 3 days before surgery (T1) and 2 months (T2) and 1 year (T3) after surgery.
Results:
A cross-lagged path analytic model showed that an increase in depressive symptoms predicted a decrease in physical functioning (β(T)₁₋(T)₂ = -0.15 [P < .001]; β(T)₂₋(T)₃= -0.17 [P < .001]), but not the other way around. Multigroup comparisons revealed one moderator effect: in patients with systolic heart failure (left ventricular ejection fraction [LVEF], ≤45%), the effect of depression on physical functioning from T2 to T3 was significantly stronger than in patients with preserved LVEF (β(T)₂₋(T)₃= -0.30 [P < .001] vs β(T)₂₋(T)₃= -0.14 [P < .001]; χ²(diff) = 3.885 [P = .049]).
Conclusions:
More attention should be paid to diagnosis and treatment of depression in patients undergoing CABG. After surgery, patients with systolic heart failure and depressive symptoms in particular seem at risk of a deterioration of their physical functioning.
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