[Taurine-activated currents in isolated neurons of the rat cerebellum]

Taurine-activated currents in isolated neurons of the rat cerebellum were studied by voltage and "concentration" clamp methods. They were transmitted by potassium and chloride ions. The dose-response curve with the dissociation constant 2 x 10(-3) mol/l was obtained. The cross-desensitization between taurine and GABA, but not between taurine and glycine was shown. These currents were also blocked by bicucullin and strychnine, but in a different manner.