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During the 1950s, the landmark Robbers Cave experiment demonstrated that when groups must compete with one another, intergroup conflict, hostility, and even violence may result. At the Oklahoman summer camp, two troops of boys—termed the Rattlers and the Eagles—took part in a week-long tournament. During this time, their negativity culminated in derogatory name-calling, fistfights, and even vandalism and destruction of property. However, this work also revealed that such tension could be...
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Related Experiment Video

Updated: Jun 7, 2026

Assessment of Social Cognition in Non-human Primates Using a Network of Computerized Automated Learning Device (ALDM) Test Systems
08:42

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Fifth Alon Dembo memorial workshop: case 3.

Peter E Schwartz1

  • 1Yale University School of Medicine, New Haven, CT 06520, USA. peter.schwartz@yale.edu

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
|October 27, 2010
PubMed
Summary
This summary is machine-generated.

Monitoring ovarian cancer patients with serial CA-125 levels is crucial for early detection of recurrence. Prompt intervention based on rising CA-125 can improve outcomes in high-risk individuals.

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Area of Science:

  • Oncology
  • Gynecologic Oncology
  • Cancer Biomarkers

Background:

  • Critique of the OVO5/EORTC 55855 study's limitations in evaluating CA-125 for ovarian cancer follow-up.
  • OVO5/EORTC 55855 suffered from a heterogeneous patient population and lack of control over treatment regimens.
  • Recent evidence suggests roles for surgery, tamoxifen, and platinum doublets in recurrent ovarian cancer, which were not considered in OVO5/EORTC 55855.

Purpose of the Study:

  • To highlight the importance of continued monitoring of ovarian cancer patients post-treatment.
  • To emphasize the role of CA-125 in identifying early signs of recurrence.
  • To advocate for proactive treatment initiation based on biomarker trends.

Main Methods:

  • Case presentation of an advanced ovarian cancer patient with a high initial CA-125 level.
  • Initial treatment included surgery followed by chemotherapy.
  • Patient achieved normal CT scan and CA-125 levels post-chemotherapy.

Main Results:

  • The patient, despite initial treatment success, remains at high risk for recurrence.
  • Serial CA-125 monitoring is proposed as a key strategy.
  • Early detection of recurrence via CA-125 may allow for timely intervention.

Conclusions:

  • Continued surveillance with serial CA-125 measurements is recommended for high-risk ovarian cancer patients.
  • Initiating treatment based on rising CA-125 levels, even before clinical symptoms, is advised.
  • This approach aims to improve management of recurrent ovarian cancer.