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Published on: February 14, 2012
Diagnostic and Pathophysiological Impact of Myocardial MIBG Scintigraphy in Parkinson's Disease
1Department of Neurology, Saarland University, Kirrberger Straße, 66421 Homburg/Saar, Germany.
Abstract:
Myocardial MIBG scintigraphy is established in the diagnosis and differential diagnosis of Parkinson's disease (PD). Numerous studies address the pathophysiological impact of myocardial MIBG scintigraphy: the myocardial MIBG uptake correlates with the clinical phenotype of PD; the background of this phenomenon is unclear. Furthermore MIBG scintigraphy enables to study the extracranial Lewy body type-degeneration. In combination with cerebral dopamine transporter imaging, MIBG scintigraphy allows to correlate cerebral and extracranial Lewy body type-degeneration in PD.
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