Radiotherapy for multiple myeloma with skin involvement

Area of Science:

• Oncology
• Dermatology

Background:

• Multiple myeloma is a cancer of plasma cells.
• Skin metastasis from multiple myeloma is uncommon and signifies advanced disease.

Purpose of the Study:

• To report a rare case of multiple myeloma with cutaneous involvement.
• To discuss the management and outcome of this rare presentation.

Main Methods:

• Case report of a patient with known multiple myeloma.
• Utilized limited-field radiation treatment for tumor debulking.

Main Results:

• The patient presented with cutaneous lesions on the right leg.
• Radiation treatment successfully reduced tumor bulk.
• The patient unfortunately died from systemic treatment complications.

Conclusions:

• Cutaneous involvement in multiple myeloma is a sign of high tumor burden.
• While localized treatment can help debulk tumors, systemic disease progression and treatment complications remain significant challenges.