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Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
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Problems and outcome of Hirschsprung's disease presenting after 1 year of age in a developing country

S O Ekenze1, C Ngaikedi, A A Obasi

  • 1Sub-Department of Paediatric Surgery, University of Nigeria Teaching Hospital, Enugu, Nigeria. sebekenze@gmail.com

World Journal of Surgery
|October 27, 2010
PubMed

Insights

Delayed diagnosis of Hirschsprung

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Public Health

Background:

  • Hirschsprung's disease (HD) diagnosis is often delayed in resource-limited settings.
  • Late presentation of HD leads to significant complications and increased morbidity.

Purpose of the Study:

  • To evaluate problems, treatment outcomes, and factors contributing to delayed Hirschsprung's disease presentation after one year of age.
  • To identify challenges in managing Hirschsprung's disease in a resource-limited environment.

Main Methods:

  • Retrospective study of 41 children over 1 year old with Hirschsprung's disease.
  • Data collected from January 2000 to June 2009 at University of Nigeria Teaching Hospital, Enugu.

Main Results:

  • 92.7% of children presented with complications.
  • Late presentation attributed to delayed referral (65.9%), parental ignorance (26.8%), and poverty (7.3%).
  • High colostomy rates (85.4%) and postoperative complications (48.8%) were observed. Good outcomes achieved in 75.6%.

Conclusions:

  • Hirschsprung's disease presenting late is linked to high colostomy rates and morbidity.
  • Improved diagnosis requires enhanced medical practitioner education and public awareness campaigns.
Abstract

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