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Updated: Jun 7, 2026
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Grafting of Beads into Developing Chicken Embryo Limbs to Identify Signal Transduction Pathways Affecting Gene Expression
Published on: January 17, 2016
FGF signalling: diverse roles during early vertebrate embryogenesis
1The Healing Foundation Centre, Michael Smith Building, Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
Development (Cambridge, England)
|October 28, 2010
Summary
Fibroblast growth factor (FGF) signaling is crucial for early vertebrate development, guiding embryonic axis patterning and cell lineage formation. This review summarizes FGF
Area of Science:
- Developmental Biology
- Cell Signaling
Background:
- Fibroblast growth factor (FGF) signaling plays a critical role in embryonic development.
- FGF signaling is involved in various developmental processes, including axis patterning, cell lineage specification, and morphogenesis.
Purpose of the Study:
- To summarize the current understanding of FGF signaling regulation and roles in early vertebrate development.
Main Methods:
- Literature review and synthesis of existing research on FGF signaling in embryogenesis.
Main Results:
- FGF signaling is essential for establishing embryonic axes.
- FGF signaling regulates the induction and maintenance of multiple cell lineages.
- FGF signaling coordinates morphogenetic movements during development.
Conclusions:
- FGF signaling is a key regulator of early vertebrate embryogenesis.
- Further research is needed to fully elucidate the complex regulatory mechanisms and diverse roles of FGF signaling.
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