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Related Experiment Video

Updated: Jun 7, 2026

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer

Published on: October 31, 2025

Updated recommendations for breast cancer screening.

Kimberly D Gregory¹, George F Sawaya

¹Women's Healthcare Quality & Performance Improvement, Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. gregory@cshs.org

Current Opinion in Obstetrics & Gynecology

|October 28, 2010

Summary

New U.S. Preventive Services Task Force (USPSTF) guidelines recommend biennial mammography for women aged 50-74 for maximal breast cancer mortality benefit. Starting screening at age 40 offers a small additional benefit, with the decision being personalized.

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Last Updated: Jun 7, 2026

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer

Published on: October 31, 2025

Area of Science:

Oncology
Preventive Medicine
Radiology

Background:

The U.S. Preventive Services Task Force (USPSTF) periodically updates evidence-based screening recommendations.
Breast cancer remains a significant public health concern, necessitating regular review of screening protocols.

Purpose of the Study:

To elucidate the evidence-based rationale for the USPSTF's latest breast cancer screening recommendations.
To summarize the benefits and harms associated with various breast cancer screening modalities.

Main Methods:

Systematic review of evidence on screening benefits and harms, including radiation exposure and false-positive rates.
Analysis of data from the Oregon Evidence-based Practice Center and the Cancer Intervention Surveillance and Modeling Network.
Evaluation of randomized trials concerning breast self-examination and clinical breast examination.

Main Results:

Biennial mammography screening from age 50 to 74 maximizes mortality reduction with minimal harms.
Screening initiation at age 40 yields a marginal increase in benefit.
Evidence does not support routine breast self-examination or clinical breast examination for screening.

Conclusions:

The optimal age to commence biennial mammography screening is 50, extending to age 74.
Individualized decisions regarding earlier screening (age 40) should weigh personal values against potential harms.
Current evidence does not support routine clinical breast examination or teaching breast self-examination for screening purposes.