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Related Experiment Video

Updated: Jun 7, 2026

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization

Published on: June 4, 2020

Critical factors contributing to the thromboelastography trace.

Stephen G MacDonald¹, Roger J Luddington

¹Haemostasis Unit, Haematology Department, Addenbrooke's Hospital, Cambridge, United Kingdom.

Seminars in Thrombosis and Hemostasis

|October 28, 2010

Summary

Thromboelastography (TEG) analyzes blood

Area of Science:

Hemostasis and thrombosis research
Point-of-care diagnostics
Clinical pathology

Background:

Thromboelastography (TEG) provides a graphical and numerical analysis of blood viscoelastic changes.
The TEG trace is influenced by cellular components, fibrinogen, coagulation factors, and pharmacological agents.
Historically, TEG has guided blood component transfusions, particularly in cardiac and hepatic surgery.

Purpose of the Study:

To provide a comprehensive overview of thromboelastography applications.
To examine factors influencing TEG trace characteristics.
To explore emerging uses in pharmaceutical monitoring and patient screening.

Main Methods:

Review of existing literature on thromboelastography.
Analysis of factors affecting TEG trace interpretation (preanalytical, analytical, clinical).

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A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

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A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

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Discussion of current and novel applications of TEG technology.

Main Results:

TEG is a versatile tool reflecting the complex hemostatic system.
Trace characteristics are sensitive to a wide array of physiological and pathological conditions.
TEG's utility is expanding beyond traditional surgical settings.

Conclusions:

Thromboelastography is a valuable point-of-care technology for assessing hemostasis.
Understanding influencing factors is crucial for accurate interpretation.
New applications in drug monitoring and patient screening show significant promise.