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Incidence of cleft lip and palate in Uganda
Insights
The incidence of oral-facial clefts in Uganda is 0.73 per 1000 births. This study estimates the need for 1800 cleft repairs annually, highlighting resource allocation requirements for effective treatment.
Area of Science:
- Pediatric Surgery
- Public Health
- Genetics
Background:
- Oral-facial clefts are common congenital anomalies requiring surgical intervention.
- Accurate incidence data is crucial for healthcare resource planning in developing nations.
Purpose of the Study:
- To determine the incidence of oral-facial clefts in Uganda.
- To analyze the ratio of different cleft types (cleft lip, cleft palate, cleft lip and palate).
- To estimate the demand for cleft repair surgeries in Uganda.
Main Methods:
- A 1-year prospective study conducted in seven hospitals in Kampala, Uganda.
- Examination of all live-born neonates for oral-facial clefts within 24 hours of delivery.
- Collection of monthly maternity data to establish the birth population denominator.
Main Results:
- A total of 26,186 births were recorded over the study period.
- The incidence of oral-facial clefts was found to be 0.73 per 1000 births.
- Cleft lip and palate occurred in 63.2% of cases, isolated cleft lip in 31.2%, and isolated cleft palate in 5.3%.
Conclusions:
- The incidence of oral-facial clefts in Uganda is estimated at 0.73 per 1000 births.
- An estimated 1100 babies born with clefts annually require approximately 1800 surgical repairs.
- These findings provide essential data for advocating and planning resources for cleft treatment in Uganda.
Objective:
The purpose of the study was to estimate the need for resources for cleft repairs in Uganda by determining the overall incidence of oral-facial clefts and the ratio of isolated cleft lip to isolated cleft palate to cleft lip and palate.
Design:
A 1-year prospective study was implemented in seven hospitals and health centers with maternity units in and around Kampala. All live babies were examined for cleft lip and/or palate at birth. The birth of a baby with a cleft was communicated to the research coordinator by maternity staff, and the babies were assessed within 24 hours of delivery. Maternity data (live births) for each center were collected monthly to determine the denominator.
Results:
Over the course of 1 year (February 1, 2008 to January 31, 2009), 26,186 babies were delivered. Nineteen babies had a cleft lip and/or palate, giving an incidence of 0.73 in 1000; 12 of the 19 babies (63.2%) had a cleft lip and palate, six (31.2%) had an isolated cleft lip, and only one (5.3%) had an isolated cleft palate. The ratio of boys to girls was 1.1∶1.
Conclusions:
The incidence of clefts in this study was 0.73 in 1000. With an estimated 1100 babies born with a cleft per year, this would result in the need for 1800 cleft repairs for babies in Uganda (695 babies needing two repairs each). These data will be helpful to advocate for and plan the necessary resources to effectively treat this condition.
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