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Published on: April 13, 2015
[Relationship between red cell volume distribution width and cardiac function in acute coronary syndrome patients]
Ming-hua Zhang1, Hua Zhang, Ji-hong Zhao
1Department of Clinical Laboratory, Affiliated Hospital of Medical College of Chinese People's Armed Police Force, Tianjin 300162, China.
Objective:
To evaluate the relationship between red cell volume distribution width (RDW) and cardiac function in acute coronary syndrome (ACS) patients.
Methods:
We analyzed the baseline clinical data of 228 ACS patients consecutively admitted into our hospital according to the classification of RDW and NYHA function class. Correlation analysis was made respectively between RDW and plasma creatinine and left ventricular ejection fraction (LVEF).
Results:
There were significant differences of age [Group Q(1) to Group Q(4): (60 ± 12), (65 ± 11), (64 ± 11), (71 ± 12) years old], plasma creatinine [Group Q(1) to Group Q(4): (70 ± 19), (76 ± 24), (74 ± 20), (85 ± 26) µmol/L] and LVEF [Group Q(1) to Group Q(4): (57 ± 9)%, (55 ± 10)%, (53 ± 11)%, (49 ± 11)%] among different RDW groups (P = 0.0000, 0.0054, 0.0002, respectively). Comparing to NYHA function I, patients of NYHA function IV had a higher RDW (13.9% ± 1.2% vs 13.1% ± 5.7%, P < 0.05). There were significant negative correlations between RDW and LVEF (r = -0.30, P < 0.01).
Conclusion:
RDW may be significantly related to cardiac function in Chinese ACS patients.
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