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Updated: Jun 7, 2026

Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors
Published on: March 29, 2019
[Multivariate analysis of recurrence factors for non muscle-invasive bladder urothelial carcinomas]
Jun-xing Chen1, Nan Deng, Ling-wu Chen
1Department of Urology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China. junxingchen@hotmail.com
Objective:
To discuss the risk factors of recurrent non-muscle-invasive bladder cancer and elucidate its clinical significance.
Methods:
The retrospective survival analysis of 161 patients with non-muscle-invasive bladder cancer was performed by Kaplan-Meier method, Log-rank test and COX proportional hazard model.
Results:
On univariate analysis, the parameters of tumor stage, tumor grade, number of tumors and previous recurrence were significant for tumor recurrence (all P < 0.05). On multivariate analysis of COX proportional hazard model, all the above risk factors remained significant for tumor recurrence. The hazard ratios were as follows: tumor stage (RR = 3.810, P = 0.001), tumor grade (RR = 2.416, P = 0.009), number of tumors (RR = 1.736, P = 0.036) and previous recurrence (RR = 1.810, P = 0.010).
Conclusion:
Tumor stage and tumor grade plays the most important role in tumor recurrence.
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