Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...

Chronic Kidney Disease III: Interprofessional Care

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...

Chronic Kidney Disease IV: Nursing Management

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of fluid...

Diabetic Nephropathy

Diabetic Nephropathy

Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Structural analysis of lipooligosaccharide produced by Neisseria gonorrhoeae, strain MS11mk (variant A): a precursor for a gonococcal lipooligosaccharide associated with virulence.

Biochemistry·1992

Same author

[Surveillance of the incidence of diabetes mellitus in a rural area of Mecklenburg-Vorpommern].

Zeitschrift fur arztliche Fortbildung·1992

Same author

Vascular beta-adrenoceptor-mediated responses in hypertension and ageing in rats.

Journal of autonomic pharmacology·1992

Same author

27Al satellite transition spectroscopy (SATRAS) of polycrystalline aluminum borate 9Al2O3.2B2O3.

Solid state nuclear magnetic resonance·1992

Same author

[Acute intermittent porphyria in pregnancy: glucose or hematin therapy?].

Schweizerische medizinische Wochenschrift·1992

Same author

[Induction of labor with a new intracervically administered prostaglandin E2 gel. Report of initial experience].

Geburtshilfe und Frauenheilkunde·1992

Search research articles

Related Experiment Video

Updated: Jun 7, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

Is there a need for early detection programs for chronic kidney disease?

I J Katz¹, T E Gerntholtz, M van Deventer

¹Dumisani Mzamane African Institute of Kidney Disease, Soweto, University of the Witwatersrand, South Africa. ivorjkatz@gmail.com

Clinical Nephrology

|October 29, 2010

Summary

Early detection programs are needed for chronic kidney disease (CKD) management. Screening can integrate CKD care with common illnesses, offering clinical and cost-effective benefits for CKD and cardiovascular disease.

More Related Videos

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats

Published on: March 11, 2016

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

Related Experiment Videos

Last Updated: Jun 7, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats

Published on: March 11, 2016

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

Area of Science:

Nephrology
Public Health
Epidemiology

Background:

Chronic kidney disease (CKD) and its risk factors (hypertension, diabetes, HIV) pose significant global health challenges.
CKD prevalence is substantial in both developing and developed nations.
Early detection and treatment of CKD are feasible with minor practice adjustments.

Purpose of the Study:

To determine the necessity of early detection programs for managing chronic kidney disease (CKD).
To evaluate if CKD meets epidemiological criteria for justifying early screening.
To assess the challenges and capacity for establishing CKD early detection programs.

Main Methods:

Literature review of existing materials on CKD prevalence and risk factors.
Epidemiological evaluation of CKD to justify screening criteria.
Assessment of challenges and existing capacity for early detection programs.

Main Results:

Growing evidence indicates significant CKD prevalence worldwide.
CKD is detectable and treatable with minor modifications to current practices.
Screening programs offer potential improvements in CKD detection and management.

Conclusions:

Early detection programs for CKD are warranted, despite a lack of randomized trials.
These programs can integrate CKD management with prevalent chronic diseases.
Integrated management offers clinical and cost-effective benefits for CKD and cardiovascular disease.