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Antitumor activity of methyl-4 H-1,2,4-benzothiadiazin-3-yl-carbamodithioate-S,S,-dioxide
1Dipartimento di Scienze Farmaceutiche, University of Modena, Italy.
Bollettino Chimico Farmaceutico
|September 1, 1990
Abstract:
The antitumor activity of the methyl-6-chloro-4H-1,2,4-benzothiadiazin-3-yl-S-carbamothioate+ ++-S,S,-dioxide (1) and the methyl-4H-1,2,4-benzothiadiazin-3-yl-carbamodithioate-S,S-di oxide (2), has been evaluated. Compound 2 passed activity criteria for leukemia P388 and was also moderately active against transplanted mouse tumor L1210 leukemia and M5076 sarcoma.