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Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
Published on: November 2, 2013
Screening for prostate cancer: a controversy or fact
Hippokratia
|October 29, 2010
Summary
Prostate cancer screening aims for early detection but its effectiveness remains unproven. Definitive evidence requires demonstrating a reduction in prostate cancer mortality rates through screening initiatives.
Area of Science:
- Oncology
- Urology
- Public Health
Background:
- Prostate adenocarcinoma is a prevalent male malignancy and a significant cause of cancer death globally.
- Early prostate cancer detection through screening facilitates management with various therapeutic options.
Purpose of the Study:
- To critically evaluate the rationale and evidence supporting clinical decisions on prostate cancer screening for early detection in men.
- To analyze the advantages and disadvantages associated with prostate cancer screening protocols.
Main Methods:
- Comprehensive literature search using MEDLINE and manual review of bibliographies.
- Analysis and synthesis of findings from relevant studies on prostate cancer screening.
- Examination of screening methods, schedules, and their associated benefits and drawbacks.
Main Results:
- Despite numerous studies, few provide conclusive evidence regarding the efficacy of prostate cancer screening.
- A review of screening modalities, timing, and the pros and cons of prostate cancer screening was conducted.
Conclusions:
- The established role of prostate cancer screening in reducing mortality is yet to be confirmed.
- A definitive benefit of screening would be demonstrated by a measurable decrease in prostate cancer death rates attributable to screening efforts.
