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Biological activity of two photoactive benzocoumarins
C Dianzani1, L Silvestro, I Viano
1Institute of Pharmacology and Experimental Therapy, University of Turin, Italy.
International Journal of Tissue Reactions
|January 1, 1990
Abstract:
The effect on DNA synthesis in cell cultures exerted by two photoactive benzocoumarins were studied. A favourable ratio between inhibition of DNA synthesis and the irradiation time periods was found in these compounds. This activity is substantially due to their ability to produce a monofunctional adduct with DNA.