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Role of autocrine stimulation in a glioma cell line
1Dipartimento di Science Neurologiche, Neurochirurgia, Università degli Studi di Roma La Sapienza, Italy.
Journal of Neurosurgical Sciences
|July 1, 1990
Abstract:
It has recently been shown that autocrine stimulation can play a pivotal role in the development and progression of a variety of neoplasms, including malignant gliomas. In this paper is reported how a glioma cell is able to be stimulated by basic fibroblast growth factor (bFGF) and, at the same time, to produce a growth factor which shares with bFGF many biological and biochemical properties.