[The immune response and its dynamic changes of anti-HBs in 98 juveniles vaccinated with native hepatitis B vaccine]

The immune response and its dynamic changes of anti-HBs in 98 Juveniles vaccinated with three doses of native plasma derived HB vaccine (have been were studied and) followed up for three years. The results showed that the cumulative positive rate and its mean S/N values of anti-HBs at T1 were 70.41% and 19.89 respectively, at T3, T6, T12, T24 all 98% and 65.54, 41.75, 53.95, 23.79 respectively. However out of 98 mentioned recipients 18 subjects become negative for anti-HBs at T36.