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[Bacteremia and fungemia in patients with AIDS. Study of 56 episodes]
1Servicio de Medicina Interna-Patología Infecciosa, Hospital General Vall d'Hebron, Universidad Autónoma de Barcelona.
Abstract:
We report 56 episodes of bacteremia and fungemia in 45 patients (23%) out of overall 193 cases of AIDS. 41% of the isolates were gram-negative bacilli, with a predominance of Salmonella enteritidis (30%), most of them community-acquired. Gram-positive cocci (18 episodes) were hospital-acquired in 61%, with a predominance of Staphylococcus sp (10 cases). Mycobacteria and Cryptococcus neoformans were isolated in 8 patients. 88.8% of our patients with cryptococcosis (8/9) had positive blood cultures. 76% of the episodes (43/56) were community-acquired, with a high incidence of primary bacteremias (59%). 48% of the patients were cured, whereas 27% died from causes related with the bacteremia.
Insights
In patients with Acquired Immunodeficiency Syndrome (AIDS), bloodstream infections (bacteremia and fungemia) were common, often caused by community-acquired Salmonella and hospital-acquired Staphylococcus. Fungal infections like cryptococcosis also presented significant challenges.
Area of Science:
- Infectious Diseases
- Clinical Microbiology
- Immunology