[Possible effects of pharmacologic prophylaxis for Mendelson's syndrome on newborns]

Forty-eight newborn infants whose mothers underwent both elective and urgent caesarean section were studied. Mothers were randomly assigned to one of the treatment groups for the prophylaxis of Aspiration Pneumonitis: group A was treated with ranitidine, 50 mg i.v.; group B with ranitidine, 50 mg, and metoclopramide, 10 mg i.v.; group C no medication. Neonatal assessment included Apgar score and various haematological laboratory tests: haemogasanalysis, glycemia, electrolites, hematocrit, hemoglobin, bilirubinemia, SGOT, SGPT. Nor clinical or statistic differences were noted among the three infant groups.