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Policies for the prevention of coronary heart disease through cholesterol-lowering
1Lipid Metabolism-Atherogenesis Branch National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Abstract:
Policies for coronary heart disease prevention through cholesterol-lowering have been advocated by groups in the UK, the US and Continental Europe. Such policies are based on studies of the atherosclerotic plaque, experimental animals, genetic disorders, and lipoprotein metabolism, and from different epidemiological studies and clinical trials. Surveys of physicians and the public indicate a growing awareness of the importance of cholesterol. Expert groups advocate mutually compatible high-risk and population-based strategies. Selective or whole adult population screening is being discussed as is whether it should be done exclusively in the doctor's office or should also include mass public screening. Improved standards for public screening are necessary. The US National Cholesterol Education Program has developed or is developing reports on: (1) the detection, evaluation and treatment of high blood cholesterol in (a) adults and (b) children and adolescents; and on (2) standardization of cholesterol measurement and (3) population-based strategies for controlling cholesterol.
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