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The development of the retinal projection to the olivary pretectal nucleus in normal and monocularly enucleated
1Departamento de Fisiologia e Farmacologia, Universidade Federal de Pernambuco, Recife, Brasil.
Abstract:
The projection to the olivary pretectal nucleus (OPN) from the contralateral eye is observed on the first day after birth and appears adult-like on postnatal day 5. The ipsilateral projection is present at postnatal day 4, and expands to fill the nucleus overlapping the contralateral projection, though never as dense, between days 6 and 8. Then, in normal hamsters, ipsilaterally projecting fibers retract to the ventral side of the OPN by day 10. However, the dense expanded projection in the dorsal OPN ipsilateral to the remaining eye in monocularly enucleated hamsters persists into adulthood.