Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Risk factors in amblyopia.

J Sjöstrand1, M Abrahamsson

  • 1Department of Ophthalmology, Sahlgren's Hospital, University of Göteborg, Sweden.

Eye (London, England)
|January 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

5 a longitudinal study of a population based sample of astigmatic children. 1. Refraction and amblyopia.

Strabismus·2011
Same author

Optical properties of diffractive, bifocal, intraocular lenses.

Applied optics·2010
Same author

SURFACE STRUCTURE OF ISOLATED NEURONS : Detachment of Nerve Terminals during Axon Regeneration.

The Journal of cell biology·2009
Same author

Potential protective effects of NSAIDs/ASA in oxidatively stressed human lens epithelial cells and intact mouse lenses in culture.

Ophthalmic research·2005
Same author

Subnormal visual acuity (SVAS) and albinism in Mexican 12-13-year-old children.

Documenta ophthalmologica. Advances in ophthalmology·2004
Same author

A new model for assessing proteolysis in the intact mouse lens in organ culture.

Ophthalmic research·2004
Same journal

The NHS Diabetic Eye Screening Programme: Insights from a Research and Innovation Needs Assessment.

Eye (London, England)·2026
Same journal

Socioeconomic inequalities in self-reported vision impairment among middle-aged and older adults in China: a national longitudinal study from 2011 to 2018.

Eye (London, England)·2026
Same journal

Advanced glaucoma without cupping in the setting of large optic disc drusen and high myopia.

Eye (London, England)·2026
Same journal

The giant behind the swollen disc: bilateral papilloedema heralding a silent brain tumour in tuberous sclerosis complex.

Eye (London, England)·2026
Same journal

Anterior chamber cholesterolosis in advanced Coats disease.

Eye (London, England)·2026
Same journal

Digital microscopy of demodex microbubble encirclement after lotilaner 0.25.

Eye (London, England)·2026
See all related articles

Early detection of amblyopia (lazy eye) risk factors in children is crucial. Identifying constant or increasing astigmatism and anisometropia between ages one and four can predict lazy eye development, enabling timely intervention.

Area of Science:

  • Ophthalmology
  • Developmental Pediatrics
  • Public Health

Background:

  • Preventing serious amblyopia (lazy eye) requires understanding normal versus subnormal visual development.
  • Predicting amblyopia risk in children depends on identifying key risk factors like refractive errors that initiate squint or amblyopia.
  • Longitudinal studies are essential for defining these risk factors and tracking visual development.

Purpose of the Study:

  • To define risk factors for amblyopia development in young children using longitudinal data.
  • To identify characteristics of refractive errors, such as astigmatism and anisometropia, associated with amblyopia.
  • To determine the optimal age for population screening to detect and treat amblyopia effectively.

Main Methods:

  • Longitudinal study of 310 children from one to four years of age with astigmatism ≥ 1.0 D at one year.

Related Experiment Videos

  • Yearly refraction measurements to track changes in astigmatism and anisometropia.
  • Analysis of refractive error variability and identification of 'at-risk' children based on constant or increasing abnormalities.

    • Main Results:

    • Astigmatism and anisometropia showed high variability in infancy and early childhood.
    • Children exhibiting constant or increasing astigmatism or anisometropia between ages one and four were identified as 'at risk' for amblyopia.
    • Longitudinal follow-up is necessary to distinguish normal refractive development from abnormal patterns leading to amblyopia.

    Conclusions:

    • A population screening at four years of age is recommended in Sweden for early detection and successful treatment of most amblyopia cases.
    • Identifying children with specific refractive error patterns during early childhood allows for targeted interventions.
    • Understanding refractive development trajectories is key to preventing severe visual impairment from amblyopia.