[Systemic candidiasis in intensive care patients after antibiotic therapy]

The authors report fluconazole treatment of 19 I.C.U. patients in critical situations. 9 of these patients had septic multiorgan failure. All patients had received long term antibiotic treatment for at least seven days. The difficulties in clinical and laboratory diagnosis of systemic candidosis which requires treatment are discussed. All patients showed good response to fluconazole treatment concerning the opportunistic mycotic infection; none of the patients died because of systemic candidosis. Severe side effects were not observed.