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Microdissection and microcloning of human banded chromosomes
1INSERM U301, Institut de Génétique Moléculaire, Paris, France.
Nouvelle Revue Francaise D'Hematologie
|January 1, 1990
Abstract:
A new microdissection and microcloning procedure of human banded chromosomes has been recently described. These microtechniques allow the construction of band-specific DNA libraries, providing a large number of DNA probes for the identification of gene sequences. These methodologies are particularly efficient to reach chromosomal regions involved in human genetic diseases including cancer.