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Updated: Aug 14, 2026

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
Published on: October 14, 2016
[Clinical features and treatment of osteogenic sarcoma of the jaws]
1Klinik und Poliklinik für Mund-Kiefer-Gesichtschirurgie, Universität, Heidelberg.
Abstract:
24 patients with osteogenic sarcomas of the jaws were entered in a retrospective study. 79.2% of the cases had local relapses or distant metastases, usually within the first 2 years following surgery. With primary surgical treatment the 5 year disease free survival rates in cases with maxillary manifestations ranged at 22.1% and with mandibular sarcomas at 18.2%. Thus, prognosis for osteogenic sarcomas of the jaws is to be assessed as being no more favorable than for sarcomas of the extremities. A review of the literature shows that aggressive pro- and postoperative chemotherapy must be postulated apart from radical tumor resection to improve the survival rates.
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