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Permanent brain damage possibly caused by theophylline in two elderly patients with airway obstruction
K Sekizawa1, T Aikawa, M Yanai
1Department of Geriatric Medicine, Tohoku University School of Medicine, Sendai.
The Tohoku Journal of Experimental Medicine
|December 1, 1990
Abstract:
Two aged patients with bronchial asthma and chronic obstructive pulmonary disease who suffered convulsions that resulted in permanent brain damage during treatment with the recommended therapeutic dose of theophylline are presented here. A dose or concentration of theophylline lower than the recommended one should be considered in the treatment of some aged patients with pulmonary obstructive disease.