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Multiple myeloma associated with amyloidosis and t(1;20)(q21;q11) translocation
K Otokida1, H Yoshida, Y Mizunuma
1Second Department of Internal Medicine, Iwate Medical University School of Medicine, Morioka.
The Tohoku Journal of Experimental Medicine
|December 1, 1990
Abstract:
A 59-year-old woman with nephrotic syndrome was diagnosed as having primary amyloidosis based on the detection of amyloid deposition (AL-protein) in the esophagus and kidneys. Bone marrow aspirate showed plasmocytic proliferation, leading to a diagnosis of multiple myeloma (IgG lambda-type). In addition, a very rare translocation t(1; 20) (q21; q11) was seen by chromosomal analysis of both the bone marrow and peripheral blood.